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Tuesday, May 04, 2010

IGF resume

igf dipengaruhi nutrisi terutama protein
dio proteinx rendah shg tdk begitu  meningkatkan igf
apabila terjadi peningkatan igf pd tikus obes hanya disebabkan inflamasi
dikasi quer-->inflamasi kurang-->igf turun
masalah: kenapa pd 0q2 & cq2 naik lagi?
lemak turun-->lipoprotein turun-->protein yg bebas naik-->igf naik??
??dosis tinggi baru tampak peran antiinflamasi quercetin??bener klo di kurva kontrol
??yang diukur elisa tu igf bebas aja ato total (+yg terikat 1gfbp) cz lycopene g pengaruh igf tp pengaruh igfbp
quercetin msk fitoestrogen g sih? cz klo iya ya memang ningkatin igf
(tp quer pny efek antiproliferatif??-->dgn ningkatin tgf)
low fat milk-->peningkatan igf krg signifikan
peran quer-igf-proliferasi tampak nyata pada pertumbuhan berlebihan (tumor, keloid)
tikus pas ditx dietx n-->inflamasi bkrg-->prolif pd bkrg-->hambatan quer krg berarti
flavonoid-->antiosteoklas-->msk hormon??
quer dosis 5-10 hambat prolif sel dg ditahan di fase G1 & hambat activity of cyclin-dependent kinases, and inhibited the phosphorylation of histone H1--> pake igf g ya
pd dm tjd penurunan igf????-->Influence of insulin-resistance on insulin-like growth factor I (IGF-1)-induced cardiac contractile response in ventricular myocytes from sucrose-fed rats.
Adding soya foods to the diet of premenopausal women does not appear to lower
serum levels of IGF-1 and IGFBP-3; if anything, the greater protein intake from soya may lead to a small increase in IGF-1 serum levels.
igfbp bisa pengaruhi pengukuran igf

--
Shigenoi Haruki

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